

This draft proposal will be released for public comment in 2021. Additionally, EPA plans to release a draft proposal on a process for selecting which NAMs will be included on future versions of the list.
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Maintain and regularly update a list of NAMs per Section 4(h)(2)(C)ĮPA published a list of NAMs in June of 2018 and committed to updating the list at least once a year.
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In 2018, EPA released a draft policy to reduce animal testing for skin sensitization. The Agency is reviewing data submitted by companies from 2015-2020 as well as the public comments received on the policy. This activity is ongoing and reflects EPA’s commitment to using NAMs for decision making in the TSCA program, when available and possible. Continue to implement NAMs to evaluate hazard, exposure and environmental fate for new and existing chemicalsĮPA has a long history of using NAMs, such as quantitative structure activity relationship (QSAR) and read-across, for hazard identification and fate characterization and modeling for exposure assessment.

A complete list of ongoing and proposed activities is detailed in Chapter 7 of the Strategic Plan.ĮPA has made important progress implementing the following near-term activities (2018-2021) in the Strategic Plan: 1.
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Additional information on reducing animal testing at EPAĮPA is working to ensure full implementation of the Strategic Plan and development and adoption of NAM approaches.Memo from Administrator Wheeler on reducing animal testing.The Strategic Plan has three core components: (1) identifying, developing and integrating NAMs for TSCA decisions (2) building confidence that the NAMs are scientifically reliable and relevant for TSCA decisions and (3) implementing the reliable and relevant NAMs for TSCA decisions. Read the Strategic Plan and associated documentation, including the initial List of Alternative Test Methods and Strategies (or New Approach Methodologies ). The Strategic Plan incorporated input from two public meetings and written comments submitted on the draft strategic plan. In 2018, EPA published its Strategic Plan to Promote the Development and Implementation of Alternative Test Methods within the TSCA Program. TSCA also requires EPA to develop a strategic plan on this topic and provide a progress report on the implementation of the plan to Congress every five years since the date of the enactment of the Lautenberg Chemical Safety Act, i.e. promote the development and timely incorporation of alternative test methods or strategies that do not require new vertebrate animal testing.reduce and replace, to the extent practicable and scientifically justified, the use of vertebrate animals in the testing of chemical substances or mixtures and.Lautenberg Chemical Safety for the 21st Century Act, directs EPA to: The Toxic Substances Control Act (TSCA), as amended by the Frank R.
